メニュー

研究

研究業績

2017年

  1. Matsushita S, Nishi K, Iwao Y, Ishima Y, Watanabe H, Taguchi K, Yamasaki K, Maruyama T, Otagiri M.
    Recombinant Human Serum Albumin Containing 3 Copies of Domain I, Has Significant in Vitro Antioxidative Capacity Compared to the Wild-Type.
    Biol Pharm Bull. 2017 40(10):1813-1817.
  2. Watanabe H, Sugimoto R, Ikegami K, Enoki Y, Imafuku T, Fujimura R, Bi J, Nishida K, Sakaguchi Y, Murata M, Maeda H, Hirata K, Jingami S, Ishima Y, Tanaka M, Matsushita K, Komaba H, Fukagawa M, Otagiri M, Maruyama T.
    Parathyroid hormone contributes to the down-regulation of cytochrome P450 3A through the cAMP/PI3K/PKC/PKA/NF-кB signaling pathway in secondary hyperparathyroidism.
    Biochem Pharmacol. 2017 145:192-201.
  3. Tabuchi R, Anraku M, Iohara D, Ishiguro T, Ifuku S, Nagae T, Uekama K, Okazaki S, Takeshita K, Otagiri M, Hirayama F.
    Surface-deacetylated chitin nanofibers reinforced with a sulfobutyl ether β-cyclodextrin gel loaded with prednisolone as potential therapy for inflammatory bowel disease.
    Carbohydr Polym. 2017 174:1087-1094.
  4. Greish K, Taha S, Jasim A, Elghany SA, Sultan A, AlKhateeb A, Othman M, Jun F, Taurin S, Bakhiet M.
    Styrene maleic acid encapsulated raloxifene micelles for management of inflammatory bowel disease.
    Clin Transl Med. 2017 6(1):28.
  5. Takeshita K, Okazaki S, Shinada K, Shibamoto Y.
    Application of a Compact Magnetic Resonance Imaging System with 1.5 T Permanent Magnets to Visualize Release from and the Disintegration of Capsule Formulations in Vitro and in Vivo.
    Biol Pharm Bull. 2017 40(8):1268-1274.
  6. Yamasaki K, Hyodo S, Taguchi K, Nishi K, Yamaotsu N, Hirono S, Chuang VTG, Seo H, Maruyama T, Otagiri M.
    Long chain fatty acids alter the interactive binding of ligands to the two principal drug binding sites of human serum albumin.
    PLoS One. 2017 12(6):e0180404.
  7. Enoki Y, Watanabe H, Arake R, Fujimura R, Ishiodori K, Imafuku T, Nishida K, Sugimoto R, Nagao S, Miyamura S, Ishima Y, Tanaka M, Matsushita K, Komaba H, Fukagawa M, Otagiri M, Maruyama T.
    Potential therapeutic interventions for chronic kidney disease-associated sarcopenia via indoxyl sulfate-induced mitochondrial dysfunction.
    J Cachexia Sarcopenia Muscle. 2017 8(5):735-747.
  8. Kawai A, Chuang VTG, Kouno Y, Yamasaki K, Miyamoto S, Anraku M, Otagiri M.
    Crystallographic analysis of the ternary complex of octanoate and N-acetyl-l-methionine with human serum albumin reveals the mode of their stabilizing interactions.
    Biochim Biophys Acta. 2017 1865(8):979-984.
  9. Yamasaki K, Enokida T, Taguchi K, Miyamura S, Kawai A, Miyamoto S, Maruyama T, Seo H, Otagiri M.
    Species Differences in the Binding of Sodium 4-Phenylbutyrate to Serum Albumin.
    J Pharm Sci. 2017 106(9):2860-2867.
  10. Taguchi K, Yamasaki K, Sakai H, Maruyama T, Otagiri M.
    The Use of Hemoglobin Vesicles for Delivering Medicinal Gas for the Treatment of Intractable Disorders.
    J Pharm Sci. 2017 106(9):2392-2400.
  11. Ikeda M, Ishima Y, Chuang VTG, Ikeda T, Kinoshita R, Watanabe H, Ishida T, Otagiri M, Maruyama T.
    Apoptosis induction of poly-S-nitrosated human serum albumin in resistant solid tumor under hypoxia can be restored by phosphodiesterase 5 inhibition.
    Nitric Oxide. 2017 69:28-34.
  12. Taguchi K, Yamasaki K, Maruyama T, Otagiri M.
    Comparison of the Pharmacokinetic Properties of Hemoglobin-Based Oxygen Carriers.
    J Funct Biomater. 2017 8(1). pii: E11.
  13. Watanabe H, Imafuku T, Otagiri M, Maruyama T.
    Clinical Implications Associated With the Posttranslational Modification-Induced Functional Impairment of Albumin in Oxidative Stress-Related Diseases.
    J Pharm Sci. 2017 106(9):2195-2203.
  14. Anraku M, Tabuchi R, Ifuku S, Nagae T, Iohara D, Tomida H, Uekama K, Maruyama T, Miyamura S, Hirayama F, Otagiri M.
    An oral absorbent, surface-deacetylated chitin nano-fiber ameliorates renal injury and oxidative stress in 5/6 nephrectomized rats.
    Carbohydr Polym. 2017 161:21-25.
  15. Sugimoto R, Watanabe H, Ikegami K, Enoki Y, Imafuku T, Sakaguchi Y, Murata M, Nishida K, Miyamura S, Ishima Y, Tanaka M, Matsushita K, Komaba H, Fukagawa M, Otagiri M, Maruyama T.
    Down-regulation of ABCG2, a urate exporter, by parathyroid hormone enhances urate accumulation in secondary hyperparathyroidism.
    Kidney Int. 2017 91(3):658-670.
  16. Setoyama H, Tanaka M, Nagumo K, Naoe H, Watanabe T, Yoshimaru Y, Tateyama M, Sasaki M, Watanabe H, Otagiri M, Maruyama T, Sasaki Y.
    Oral branched-chain amino acid granules improve structure and function of human serum albumin in cirrhotic patients.
    J Gastroenterol. 2017 52(6):754-765.
  17. T. Higashi, D. Iohara, K. Motoyama, H. Arima.
    Supramolecular Pharmaceutical Sciences: A Novel Concept Combining Pharmaceutical Sciences and Supramolecular Chemistry with Focus on Cyclodextrin-based Supermolecules.
    Chem. Pharm. Bull., in press (2017).
  18. D. Iohara, M. Okubo, M. Anraku, S. Uramatsu, T. Shimamoto, K. Uekama and F. Hirayama,
    Hydrophobically Modified Polymer/α-Cyclodextrin Thermoresponsive Hydrogels for Use in Ocular Drug Delivery.
    Mol. Pharmaceutics, 14, 2740-2748 (2017).
  19. K. Shimoishi, M. Anrakua, A. Uto, D. Iohara, F. Hirayama, D. Kadowaki, S. Zingami, T. Maruyama and M. Otagiri.
    A Comparison of the Phosphorus Content in Prescription Medications for Hemodialysis Patients in Japan.
    YAKUGAKU ZASSHI, 137, 903-908 (2017).
Page Top