メニュー

研究

研究業績

2016年

  1. Nagao S, Taguchi K, Sakai H, Yamasaki K, Watanabe H, Otagiri M, Maruyama T.
    Carbon monoxide-bound hemoglobin vesicles ameliorate multiorgan injuries induced by severe acute pancreatitis in mice by their anti-inflammatory and antioxidant properties.
    Int J Nanomedicine. 2016 11:5611-5620.
  2. Tokuno M, Taguchi K, Yamasaki K, Sakai H, Otagiri M.
    Long-Term Stored Hemoglobin-Vesicles, a Cellular Type of Hemoglobin-Based Oxygen Carrier, Has Resuscitative Effects Comparable to That for Fresh Red Blood Cells in a Rat Model with Massive Hemorrhage without Post-Transfusion Lung Injury.
    PLoS One. 2016 11(10):e0165557.
  3. Enoki Y, Watanabe H, Arake R, Sugimoto R, Imafuku T, Tominaga Y, Ishima Y, Kotani S, Nakajima M, Tanaka M, Matsushita K, Fukagawa M, Otagiri M, Maruyama T.
    Indoxyl sulfate potentiates skeletal muscle atrophy by inducing the oxidative stress-mediated expression of myostatin and atrogin-1.
    Sci Rep. 2016 6:32084.
  4. Tabuchi R, Azuma K, Izumi R, Tanou T, Okamoto Y, Nagae T, Iohara D, Uekama K, Otagiri M, Hirayama F, Ifuku S, Anraku M.
    Biomaterials based on freeze dried surface-deacetylated chitin nanofibers reinforced with sulfobutyl ether ホイ-cyclodextrin gel in wound dressing applications.
    Int J Pharm. 2016 511(2):1080-7.
  5. Nagao S, Taguchi K, Miyazaki Y, Wakayama T, Chuang VT, Yamasaki K, Watanabe H, Sakai H, Otagiri M, Maruyama T.
    Evaluation of a new type of nano-sized carbon monoxide donor on treating mice with experimentally induced colitis.
    J Control Release. 2016 234:49-58.
  6. Enokida T, Yamasaki K, Okamoto Y, Taguchi K, Ishiguro T, Maruyama T, Seo H, Otagiri M.
    Tyrosine411 and Arginine410 of Human Serum Albumin Play an Important Role in the Binding of Sodium 4-Phenylbutyrate to Site II.
    J Pharm Sci. 2016 105(6):1987-1994.
  7. Kouno Y, Anraku M, Yamasaki K, Okayama Y, Iohara D, Nakamura H, Maruyama T, Hirayama F, Kragh-Hansen U, Otagiri M.
    N-acetyl-L-methionine is a superior protectant of human serum albumin against post-translational oxidation as compared to N-acetyl-L-tryptophan.
    Biochem Biophys Rep. 2016 6:266-274.
  8. Miyamura S, Imafuku T, Anraku M, Taguchi K, Yamasaki K, Tominaga Y, Maeda H, Ishima Y, Watanabe H, Otagiri M, Maruyama T.
    Comparison of Posttranslational Modification and the Functional Impairment of Human Serum Albumin in Commercial Preparations.
    J Pharm Sci. 2016 105(3):1043-9.
  9. Fang J, Yin H, Liao L, Qin H, Ueda F, Uemura K, Eguchi K, Bharate GY, Maeda H.
    Water soluble PEG-conjugate of xanthine oxidase inhibitor, PEG-AHPP micelles, as a novel therapeutic for ROS related inflammatory bowel diseases.
    J Control Release. 2016 223:188-196.
  10. Saisyo A, Nakamura H, Fang J, Tsukigawa K, Greish K, Furukawa H, Maeda H.
    pH-sensitive polymeric cisplatin-ion complex with styrene-maleic acid copolymer exhibits tumor-selective drug delivery and antitumor activity as a result of the enhanced permeability and retention effect.
    Colloids Surf B Biointerfaces. 2016 138:128-37.
  11. Anraku M, Iohara D, Wada K, Taguchi K, Maruyama T, Otagiri M, Uekama K, Hirayama F.
    Antioxidant and renoprotective activity of 2-hydroxypropyl-ホイ-cyclodextrin in nephrectomized rats.
    J Pharm Pharmacol. 2016 68(5):608-14.
  12. Y. Inoue, D. Iohara, N. Sekiya, M. Yamamoto, H. Ishida, Y. Sakiyama, F. Hirayama, H. Arima, K. Uekama.
    Ternary Inclusion Complex Formation and Stabilization of Limaprost, A Prostaglandin E1 Derivative, in the Presence of α- and β-cyclodextrins in the solid state.
    Int. J. Pharm., 509, 338-347 (2016).
  13. D. Iohara, Y. Umezaki, M. Anraku, K. Uekama and F. Hirayama.
    In vitro and In vivo Evaluation of Hydrophilic C60OH10/2-Hydroxypropyl-β-cyclodextrin Nanoparticles as an Antioxidant.
    J. Pharm. Sci., 105, 2959-2965 (2016).
  14. K. Igami, M. Ozawa, S. Inoue, D. Iohara, T. Miyazaki, M. Shinoda, M. Anraku, F. Hirayama and K. Uekama.
    The formation of an inclusion complex between a metabolite of ginsenoside, compound K, and γ-cyclodextrin and its dissolution characteristics.
    J. Pharm. Pharmacol, 68, 608-614 (2016).
  15. T. Higashi, J. Li, X. Song, J. Zhu, M. Taniyoshi, F. Hirayama, D. Iohara, K. Motoyama and H. Arima.
    Thermoresponsive Formation of Dimethyl Cyclodextrin Polypseudorotaxanes and Subsequent One-Pot Synthesis of Polyrotaxanes.
    ACS Macro Lett., 5, 158-162 (2016).
Page Top