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研究

研究業績

2011年

  1. Fang J, Qin H, Seki T, Nakamura H, Tsukigawa K, Shin T, Maeda H.
    Therapeutic potential of pegylated hemin for reactive oxygen species-related diseases via induction of heme oxygenase-1: results from a rat hepatic ischemia/reperfusion injury model.
    J Pharmacol Exp Ther. 2011 339(3):779-89.
  2. Yukihara M, Ito K, Tanoue O, Goto K, Matsushita T, Matsumoto Y, Masuda M, Kimura S, Ueoka R.
    Effective drug delivery system for duchenne muscular dystrophy using hybrid liposomes including gentamicin along with reduced toxicity.
    Biol Pharm Bull. 2011;34(5):712-6.
  3. K. Uehata, T. Anno, K. Hayashida, K. Motoyama, T. Higashi, F. Hirayama, N. Ono , J.D. Pipkin, K. Uekama and H. Arima.
    Effects of Selected Anionic β-Cyclodextrins on Persistence of Blood Glucose Lowering by Insulin Glargine after Subcutaneous Injection to Rats.
    J. Drug Delivery, 2011, 1-9 (2011).
  4. H. Arima, T. Tsutsumi, A. Yoshimatsu, H. Ikeda, K. Motoyama, T. Higashi, F. Hirayama and K. Uekama.
    Inhibitory Effect of siRNA Complexes with Polyamidoamine Dendrimer/a-Cyclodextrin Conjugate (Generation 3, G3) on Endogenous Gene Expression.
    Eur. J. Pharm. Sci., 44(3), 375-384 (2011).
  5. T. Ishiguro, E. Morishita, D. Iohara, F. Hirayama, K. Wada, K. Motoyama, H. Arima and K. Uekama.
    Some pharmaceutical and inclusion properties of 2-hydroxybutyl-β-cyclodextrin derivative.
    Int. J. Pharm., 419(1-2), 161-169 (2011).
  6. K. Uehata, T. Anno, K. Hayashida, K. Motoyama, F. Hirayama, N. Ono, J.D. Pipkin, K. Uekama and H. Arima.
    Effect of Sulfobutyl ether-β-cyclodextrin on Bioavailability of Insulin Glargine and Blood Glucose Level after Subcutaneous Injection to Rats.
    Int. J. Pharm., 419(1-2), 71-76 (2011).
  7. Y. Miyamoto, M. Nakahara, K. Motoyama, T. Ishiguro, Y. Oda, T. Yamanoi, I. Okamoto, A. Yagi, H. Nishimura, F. Hirayama, K. Uekama and H. Arima.
    Improvement of Some Physicochemical Properties of Arundic Acid, (R)-(-)-2-Propyloctanonic Acid, by Complexation with Hydrophilic Cyclodextrins.
    Int. J. Pharm., 413(1-2), 63-72 (2011).
  8. D. Iohara, F. Hirayama, K. Higashi, K. Yamamoto and K. Uekama.
    Formation of Stable Hydrophilic C60 Nanoparticles by 2-Hydroxypropyl-β-cyclodextrin.
    Mol. Pharmaceutics, 8, 1276-1284(2011).
  9. N. Ono (nee Yoshida), Y. Miyamoto, T. Ishiguro, K. Motoyama, F. Hirayama, D. Iohara, H. Seo, S. Tsuruta, H. Arima, K. Uekama.
    Reduction of Bitterness of Antihistaminic Drugs by Complexation with β-Cyclodextrins.
    J. Pharm. Sci., 100(5), 1935-1943(2011).
  10. T. Anno, K. Motoyama, T. Higashi, F. Hirayama, K. Uekama, H. Arima.
    Preparation and Evaluation of Polyamidoamine Dendrimer (G2)/Branched-β-cyclodextrin Conjugate as a Novel Gene Transfer Carrier.
    J. Incl. Phenom. Macrocycl. Chem., 70, 339-344 (2011).
  11. K. Motoyama, Y. Mori, S. Yamashita, Y. Hayashi, H. Jono, Y. Ando, F. Hirayama, K. Uekama, H. Arima.
    In Vitro Gene Delivery Mediated by Lactosylated Dendrimer (generation 3, G3)/α-Cyclodextrin Conjugates into Hepatocytes.
    J. Incl. Phenom. Macrocycl. Chem., 70, 333-338 (2011).
  12. K. Motoyama, Y. Nakashima, Y. Aramaki, F. Hirayama, K. Uekama, H. Arima.
    In Vitro Gene Delivery Mediated by Asialofetuin-appended Cationic Liposomes Associated with γ-Cyclodextrin into Hepatocytes.
    J. Drug Delivery, 2011, 1-33 (2011).
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