Publication

研究業績

2009年

  1. K. Motoyama, K. Nagatomo, O.A.E. Soliman, F. Hirayama, K. Uekama, H. Arima,
    Potential Use of 2-Hydroxypropyl-β-cyclodextrin for Preparation of Orally Disintegrating Tablets Containing dl-α-Tocopherol Acetate, an Oily Drug,
    Chem. Pharm. Bull., 57, 1206-1212 (2009).
  2. D. Iohara, F. Hirayama, H. Kansui, H. Aoshima, S. Yamana, M. Yano, J. Kitaguchi, S. Takashima, K. Uekama,
    Preparation of Hydrophilic Nanoparticles of C60 with High Resistance to Aggregation during Storage, Using 2-Hydroxypropyl-β-cyclodextrin,
    Chem. Lett., 38, 1104-1105 (2009).
  3. K. Motoyama, K. Kameyama, R. Onodera, N. Araki, F. Hirayama, K. Uekama, H. Arima,
    Involvement of PI3K-Akt-Bad pathway in apoptosis induced by 2,6-di-O-methyl-β-cyclodextrin, not 2,6-di-O-methyl-β-cyclodextrin, through cholesterol depletion from lipid rafts on plasma membranes in cells,
    Eur. J. Pharm. Sci., 38, 249-261 (2009).
  4. T. Higashi, K. Nishimura, A. Yoshimatsu, H. Ikeda, K. Arima, K. Motoyama, F. Hirayama, K. Uekama and H. Arima,
    Preparation of Four Types of Coenzyme Q10/γ-Cyclodextrin Supramolecular Complexes and Comparison of Their Pharmaceutical Properties,
    Chem. Pharm. Bull., 57(9), 965-970 (2009).
  5. T. Higashi, F. Hirayama, S. Yamashita, S. Misumi, H. Arima and K. Uekama,
    Slow-release System of Pegylated Lysozyme Utilizing Formation of Polypseudorotaxanes with Cyclodextrins,
    Int. J. Pharm., 374 (5), 26-32 (2009).
  6. T. Higashi, F. Hirayama, S. Misumi, K. Motoyama, H. Arima and K. Uekama,
    Polypseudorotaxane Formation of Randomly-Pegylated Insulin with Cyclodextrins: Slow Release and Resistance to Enzymatic Degradation,
    Chem. Pharm. Bull., 57 (5), 541-544 (2009).
  7. K. Motoyama, H. Toyodome, R. Onodera, T. Irie, F. Hirayama, K. Uekama, H. Arima,
    Involvement of Lipid Rafts of Rabbit Red Blood Cells in Morphological Changes Induced by Methylated β-Cyclodextrins,
    Biol. Pharm. Bull., 32 (5), 700-705 (2009).
  8. K. Motoyama, Y. Hashimoto, F. Hirayama, K. Uekama, H. Arima, Inhibitory Effects of 2,6-Di-O-methyl-β-cyclodextrin on Poly I:C Signaling in Macrophages,
    Eur. J. Pharm. Sci., 35, 285-291 (2009).
  9. 上釜兼人,平山文俊,庵原大輔,
    シクロデキストリンを用いた製剤からの薬物溶出性, 吸収性の改善,
    ファルマシア, 45, 1223-1227 (2009).