Saho Goto Toshiaki Gondo Mai Takuse Moeko Yoshida Kazumi Yokomizo Jian-Rong Zhou Aya Matsunaga, Nozomi Hiraga Nobuhiro Kashige Fumio Miake Kunihiro Sumoto Heterocycles. Vol. 96(1), pp.144-151. 201729 We report the preparation of newly designed trivalent C3-symmetrical cyclic phenylboronic acid derivatives constructed on a symmetrical benzene or a cyclohexane ring. The synthesis of these C3-symmetrical molecules 44 was accomplished by an amide bond formation reaction using amino-substituted phenylboronic acid pinacol esters 22 and C3-symmetrical benzene-1,3,5-tricarboxylic acid trichloride 33a or cyclohexane-1,3,5-tricarboxylic acid trichloride 33b in the presence of Et3N. We confirmed that this procedure is conventionally applicable to the preparation of targeted C3-symmetrical cyclic boronic acid derivatives 44 in good to excellent yields. We also report the results of biological evaluation of the prepared compounds. Carbohydrate recognition of C3-symmetrical tripodal receptor-type 2,4,6-trisubstituted 1,3,5-triazine derivatives with antiviral activities Nobuko Mibu Tomonori Ohata Marina Sano Jian-Rong Zhou Kazumi Yokomizo Hatsumi Aki Kunihiro Sumoto Journal of Thermal Analysis and Calorimetry
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