崇城大学DDS研究所紀要第1巻2017年
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Shin Yasuda Masafumi Okawa Junei Kinjo Hiroyuki Miyashita Kazumi Yokomizo Hitoshi Yoshimitsu Toshihiro Nohara Nat Prod Res. Jan 20:1-5. doi: 10.1080/14786419 201729 A new resin glycoside, named calysolin XVIII (1), was isolated from the leaves, stems and roots of Calystegia soldanella Roem. et Schult. (Convolvulaceae). The structure of 1 was defined as 11S-jalapinolic acid 11-O-β-d-glucopyranosyl-(1 → 3)-O-(2-O-2S-methylbutyryl,4-O-3-hydroxy-2-methylenebutyryl)-α-l-rhamnopyranosyl-(1 → 2)-[O-β-d-glucopyranosyl-(1 → 6)-O-(34-di-O-2S-methylbutyryl)-β-d-glucopyranosyl-(1 → 3)]-O-β-d-glucopyranosyl-(1 → 2)-β-d-quinovopyranoside, intramolecular 1,2″'″'-ester on the basis of spectroscopic data. Compound 1 is the first known resin glycoside to feature 3-hydroxy-2-methylenebutyric acid as a component organic acid. In addition, 1 demonstrated an antiviral activity against herpes simplex virus type 1, with an IC50 value 2.3 μM.. ANTIVIRAL ACTIVITIES OF SOME NEW 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES HAVING ALKOXY AND/OR ALKYLAMINO GROUPS Nobuko Mibu Kazumi Yokomizo Ai Yuzuriha Marie Otsubo Yuna Kawaguchi Marina Sano Izumi Sakai Keita Nakayama Jian-Rong Zhou Kunihiro Sumoto Heterocycles. Vol.94(9), pp.1653-1677. 201729 We report the preparation of C3- and CS-symmetrical 2,4,6-trisubstituted 1,3,5-triazine

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